Low-dose methotrexate in myeloproliferative neoplasm models.
نویسندگان
چکیده
منابع مشابه
Successful treatment of hydroxyurea-associated panniculitis and vasculitis with low-dose methotrexate
INTRODUCTION Hydroxyurea is a standard treatment for myeloproliferative disorders because of its cytoreductive effects on all bone marrow cell lines. As a hydroxylated derivative of urea, it inhibits DNA synthesis by inactivating ribonucleotide diphosphate reductase. Hydroxyurea is generally well tolerated. However, a variety of cutaneous side effects including leg ulcers, dermatomyositis, and ...
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ورودعنوان ژورنال:
- Haematologica
دوره 102 9 شماره
صفحات -
تاریخ انتشار 2017